产品
编 号:F138817
分子式:C20H27NO3
分子量:329.43
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
160
In-stock
10mg
280
In-stock
25mg
392
In-stock
50mg
504
In-stock
100mg
616
In-stock
200mg
784
In-stock
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生物活性:
Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.

体内研究:
Trilostane(5.3-50 mg/kg;口服,每天 1 次,持续 3 个月) 控制狗体内垂体依赖性的高肾上腺皮质激素含量。Animal Model:Dogs with naturally-occurring pituitary-dependent hyperadrenocorticism (PDH)
Dosage:5.3-50 mg/kg
Administration:Oral administration; 5.3-50 mg/kg, once daily for 3 months
Result:Effectively achieved endocrine control with safe effects and free of side-effects.

体外研究:
Trilostane 剂量和时间依赖性地影响肾上腺皮质孕烯醇酮代谢。Trilostane 选择性地抑制肾上腺中孕烯醇酮转化为孕酮。
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