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编 号:F139386
分子式:C29H36ClNO2
分子量:466.05
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CAS No: 136647-02-4
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UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil.