产品
编 号:F149600
分子式:C22H23N5O2
分子量:389.45
产品类型
结构图
CAS No: 1394854-52-4
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产品详情
生物活性:
GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
体外研究:
GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively.