产品
编 号:F156406
分子式:C28H30F3N7O3
分子量:569.58
产品类型
结构图
CAS No: 1421227-52-2
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产品详情
生物活性:
WS3?is a novel proliferative molecule that promotes pancreatic β cell proliferation in rodent and human primary islets. WS3?can be used for the research of type 1 diabetes.
体外研究:
WS3 induces pancreatic R7T1 β cell proliferation in dose response, with an EC50 value of 0.28 μM.WS3 (1.0 nM-1.0 μM) reversibly proliferate primary retinal pigment epithelial (RPE) cells isolated from fetal and adult human donors. Following withdrawal of WS3, RPE cells differentiate into a functional monolayer, as exhibited by their expression of mature RPE genes and phagocytosis of photoreceptor outer segments.