产品
编 号:F162382
分子式:C15H17BrN4O5S
分子量:445.29
产品类型
结构图
CAS No: 1433875-14-9
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产品详情
生物活性:
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist.
体外研究:
The elimination half-life (t1/2) is approximately 16 h for Macitentan, and ACT-373898 has a similar pharmacokinetic (PK) profile to Macitentan.