产品
编 号:F164156
分子式:C20H24N10O13P2
分子量:674.41
产品类型
结构图
CAS No: 1441190-66-4
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产品详情
生物活性:
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.
体外研究:
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) contains two distinct phosphodiester linkages, one between 2′-OH of GMP and 5′-phosphate of AMP, and the other between 3′-OH of AMP and 5′-phosphate of GMP.