产品
编 号：F167713
分子式：C19H18N4O
分子量：318.37
分子式：C19H18N4O
分子量：318.37
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 1453097-13-6
产品详情
生物活性：
HUHS015 is a potent prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with an IC50 of 0.67μM for PCA-1.
体内研究：
HUHS015 potently suppresses the growth of DU145 cells in a mouse xenograft model.HUHS015 displays 7.2% bioavailability (BA) in rats after oral administration.Animal Model:Nude mice
Dosage:32 mg/kg
Administration:Subcutaneous injection; daily; 6 days
Result:Has inhibitory effect on the growth of subcutaneously implanted DU145, without limiting weight gains after a 6 days continuous administration.
体外研究：
HUHS015 significantly suppresses the growth of DU145 cells, which are human hormone-independent prostate cancer cells.
HUHS015 is a potent prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with an IC50 of 0.67μM for PCA-1.
体内研究：
HUHS015 potently suppresses the growth of DU145 cells in a mouse xenograft model.HUHS015 displays 7.2% bioavailability (BA) in rats after oral administration.Animal Model:Nude mice
Dosage:32 mg/kg
Administration:Subcutaneous injection; daily; 6 days
Result:Has inhibitory effect on the growth of subcutaneously implanted DU145, without limiting weight gains after a 6 days continuous administration.
体外研究：
HUHS015 significantly suppresses the growth of DU145 cells, which are human hormone-independent prostate cancer cells.
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